Comment by Mark Kleiman

 I’m not sure what “perfectly controlled way” means, but 90% of America’s
 cigarette smokers report that they have tried to quit and failed.
 Clearly, this failure of control cannot be attributed to prohibition.

 Even for drugs where it is true that most users do not lose control, some
 users do. Again, this is not restricted to illicit drugs, as anyone who
 has known someone in the grip of alcohol can testify. Nor is it restricted
 to the economically deprived and socially marginal. Loss of control of
 drug-taking is one of the characteristic risks of the activity, more
 prominent for some drugs and for some user types than others, but never
 entirely absent.

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